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Induction of interleukin-12 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid, deviates CD4(+) T cells from a Th2 to a Th1 response

In this study we investigated whether berberine-mediated induction of interleukin-12 (IL-12) production in antigen-presenting cells could regulate a cytokine profile of antigen-primed CD4(+) T helper (Th) cells. Pretreatment with berberine induced IL-12 production in both macrophages and dendritic c...

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Détails bibliographiques
Auteurs principaux: Kim, Tae S, Kang, Bok Y, Cho, Daeho, Kim, Seung H
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782983/
https://ncbi.nlm.nih.gov/pubmed/12807487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01673.x
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