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Characterization of extrathymic CD8αβ T cells in the liver and intestine in TAP-1 deficient mice

TAP-1 deficient (−/−) mice cannot transport MHC class I antigens onto the cell surface, which results in failure of the generation of CD8(+) T cells in the thymus. In a series of recent studies, it has been proposed that extrathymic T cells are generated in the liver and at other extrathymic sites (...

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Main Authors: Tsukada, Chika, Miyaji, Chikako, Kawamura, Hiroki, Miyakawa, Ryoko, Yokoyama, Hisashi, Ishimoto, Yuiko, Miyazawa, Shinobu, Watanabe, Hisami, Abo, Toru
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782982/
https://ncbi.nlm.nih.gov/pubmed/12807479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01654.x
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