The role of interferon-γ, nitric oxide and lipopolysaccharide in intestinal graft-versus-host disease developing in F(1)-hybrid mice

(C57BL/6 × DBA/2) F(1)-hybrid mice injected with lymphoid cells from wild-type, C57BL/6 donors develop acute, lethal graft-versus-host disease (GVHD) in which the intestine is a major target. In its destructive phase intestinal GVHD is characterized by apoptosis of intestinal crypt epithelial cells...

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Hlavní autoři: Ellison, Cynthia A, Natuik, Shannon A, Mcintosh, Alan R, Scully, Sheila A, Danilenko, Dimitry M, Gartner, John G
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782974/
https://ncbi.nlm.nih.gov/pubmed/12807491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01663.x
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