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Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the proliferation of naive CD4(+) T-helper cells by induction of FAS-independent T-cell apoptosis
CD44 is a multifunctional adhesion molecule that has been shown to be a costimulatory factor for T-cell activation in vitro and in vivo. The aim of the present study was to expand these findings by characterizing the role of CD44 during dendritic cell (DC) antigen presentation to naive, resting T ce...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782945/ https://ncbi.nlm.nih.gov/pubmed/12709015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01617.x |
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