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Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance

Interleukin-18 (IL-18), a pro-inflammatory member of the IL-1 family, has been associated with autoimmunity and allergic disease. This type of pathology is thought to be the result of a defect in immunological tolerance and is often observed in inflammatory disorders of the gut such as coeliac disea...

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Bibliographic Details
Main Authors: Eaton, Alfred D, Xu, Damo, Garside, Paul
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782890/
https://ncbi.nlm.nih.gov/pubmed/12562328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01570.x
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