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Identification of a novel gene of pyrimidine nucleotide biosynthesis, pyrDII, that is required for dihydroorotate dehydrogenase activity in Bacillus subtilis.

An in-frame deletion in the coding region of a gene of previously unidentified function (which is called orf2 and which we propose to rename pyrDII) in the Bacillus subtilis pyr operon led to pyrimidine bradytrophy, markedly reduced dihydroorotate dehydrogenase activity, and derepressed levels of ot...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Kahler, A E, Switzer, R L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178287/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8759868/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.16.5013-5016.1996
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