Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes

Insulin-like growth factor 1 receptor (IGF-1R) expression is augmented on T cells upon ligation of CD28, and this promotes IGF-1-mediated protection from Fas-induced cell death for up to 6 days. To determine the mechanism of action of IGF-1R in T-cell expansion, we investigated the signalling pathwa...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Walsh, Patrick T, Smith, Loraine M, O'Connor, Rosemary
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782831/
https://ncbi.nlm.nih.gov/pubmed/12460191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01525.x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars