Cytotoxic T lymphocyte-associated antigen-4 inhibits integrin-mediated stimulation

The negative role exerted by cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) in the regulation of T-cell activity, as induced by T-cell receptor (TCR)/CD3 and CD28 costimulation, has been widely described. In the present work we investigated the role of CTLA-4 in the control of cell activation,...

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Autori principali: Gatta, Lucia, Calviello, Gabriella, di Nicuolo, Fiorella, Pace, Luigia, Ubaldi, Vanessa, Doria, Gino, Pioli, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
Soggetti:
Tumour Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782789/
https://ncbi.nlm.nih.gov/pubmed/12383200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01493.x
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