Flavoxobin, a serine protease from Trimeresurus flavoviridis (habu snake) venom, independently cleaves Arg726-Ser727 of human C3 and acts as a novel, heterologous C3 convertase

We have recently shown that crude Trimeresurus flavoviridis (habu snake) venom has a strong capability for activating the human alternative complement system. To identify the active component, the crude venom was fractionated and purified by serial chromatography using Sephadex G-100, CM-cellulose C...

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Detalhes bibliográficos
Main Authors: Yamamoto, Chieko, Tsuru, Daisuke, Oda-Ueda, Naoko, Ohno, Motonori, Hattori, Shosaku, Kim, Sung-Teh
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782768/
https://ncbi.nlm.nih.gov/pubmed/12225369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01490.x
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