Loxosceles spider venom induces metalloproteinase mediated cleavage of MCP/CD46 and MHCI and induces protection against C-mediated lysis

We have recently shown that sphingomyelinase D toxins from the spider Loxosceles intermedia induce Complement (C) -dependent haemolysis of autologous erythrocytes by the induction of cleavage of cell-surface glycophorins through activation of a membrane-bound metalloproteinase. The aim of this study...

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Hlavní autoři: van den Berg, Carmen W, de Andrade, Rute M Gonçalves, Magnoli, Fabio C, Marchbank, Kevin J, Tambourgi, Denise V
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2002
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782767/
https://ncbi.nlm.nih.gov/pubmed/12225368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01468.x
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