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Modulation of the CD40–CD40 ligand interaction using human anti-CD40 single-chain antibody fragments obtained from the n-CoDeR phage display library

CD40 plays a central regulatory role in the immune system and antibodies able to modulate CD40 signalling may consequently have a potential in immunotherapy, in particular for treatment of lymphomas and autoimmune disease like multiple sclerosis. As a first step to achieve this goal, we describe the...

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Detalhes bibliográficos
Main Authors: Ellmark, Peter, Ottosson, Camilla, Borrebaeck, Carl A K, Malmborg Hager, Ann-Christin, Furebring, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782749/
https://ncbi.nlm.nih.gov/pubmed/12153507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01473.x
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