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A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes

During mouse B-cell development, Pax5 is an essential transcription factor that acts as an activator of B-cell-specific genes and as a repressor of alternative lineage fates. The repressive function is mediated by the recruitment of members of the Groucho co-repressor family. Using an RNA display ap...

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Detalhes bibliográficos
Main Authors: Milili, Michèle, Gauthier, Laurent, Veran, Julie, Mattei, Marie-Geneviève, Schiff, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782747/
https://ncbi.nlm.nih.gov/pubmed/12153506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01456.x
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