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Liposome/DNA complexes coated with biodegradable PLA improve immune responses to plasmid encoding hepatitis B surface antigen

We hypothesized that the addition of polymer to the surface of liposome/DNA complexes may potentially enhance in vivo delivery of plasmid DNA to antigen-presenting cells and thereby facilitate enhanced immune responses to encoded protein. BALB/c mice were immunized subcutaneously or intramuscularly...

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Détails bibliographiques
Auteurs principaux: Bramwell, Vincent W, Eyles, Jim E, Somavarapu, Satyanarayana, Alpar, H Oya
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782737/
https://ncbi.nlm.nih.gov/pubmed/12100730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01448.x
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