Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rβ2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells

The results reported herein show that T cells responding to encapsulated Cryptococcus neoformans cells had reduced expression of interleukin-12 receptor β2 (IL-12Rβ2) in comparison to those responding to non-encapsulated cells. This suggested that encapsulation with glucuronoxylomannan (GXM), the pr...

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Autori principali: Vecchiarelli, Anna, Pietrella, Donatella, Bistoni, Francesco, Kozel, Thomas R, Casadevall, Arturo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782713/
https://ncbi.nlm.nih.gov/pubmed/12047756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01419.x
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