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Lack of evidence for aggregation-dependent enhancement of p56(lck) in the signal transduction upon major histocompatibility complex recognition by mature T cells

The kinase activity of lymphocyte-specific tyrosine kinase p56(lck) (Lck) upon physiological major histocompatibility complex (MHC) recognition by normal mature T cells was examined. Recognition of the target MHC molecules by T cells induced phosphorylation of the ζ-chain without obvious enhancement...

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Main Authors: Eshima, Koji, Suzuki, Harumi, Shinohara, Nobukata
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782695/
https://ncbi.nlm.nih.gov/pubmed/11972631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01392.x
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