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Human monoclonal natural autoantibodies against the T-cell receptor inhibit interleukin-2 production in murine T cells

Natural autoantibodies (NAAbs) specific for the T-cell receptor (TCR) are present in all human sera, but individuals with rheumatoid arthritis (RA) generally produce higher titres of immunoglobulin M (IgM) isotype autoantibodies (AAbs) against Vβ TCR epitopes. To investigate possible correlations be...

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Detalhes bibliográficos
Main Authors: Robey, Ian F, Schluter, Samuel F, Akporiaye, Emmanuel, Yocum, David E, Marchalonis, John J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782677/
https://ncbi.nlm.nih.gov/pubmed/11985662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01389.x
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