Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance.

In this study, we compared metronidazole (Mtz)-sensitive and -resistant strains of Helicobacter pylori for metabolic differences that might correlate with drug resistance. Included in this study was an isogenic Mtz(r) strain, HP1107, that was constructed by transforming genomic DNA from Mtz(r) strai...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Hoffman, P S, Goodwin, A, Johnsen, J, Magee, K, Veldhuyzen van Zanten, S J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8759844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.16.4822-4829.1996
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