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In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype

We have previously shown in an in vitro study that the filarial nematode phosphorylcholine (PC)-containing glycoprotein ES-62 promotes a murine dendritic cell (DC) phenotype that induces T helper type 2 (Th2) responses. We now show that, in addition to directly priming Th2 responses, ES-62 can act t...

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Detalhes bibliográficos
Main Authors: Goodridge, Helen S, Marshall, Fraser A, Wilson, Emma H, Houston, Katrina M, Liew, Foo Y, Harnett, Margaret M, Harnett, William
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782600/
https://ncbi.nlm.nih.gov/pubmed/15554927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01993.x
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