Interleukin-5 regulates genes involved in B-cell terminal maturation

Interleukin (IL)-5 induces CD38-activated splenic B cells to differentiate into immunoglobulin M-secreting cells and undergo µ to γ1 class switch recombination (CSR) at the DNA level, resulting in immunoglobulin G1 (IgG1) production. Interestingly, IL-4, a well-known IgG1-inducing factor does not in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Horikawa, Keisuke, Takatsu, Kiyoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2006
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782313/
https://ncbi.nlm.nih.gov/pubmed/16895557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02382.x
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