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Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis

The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12. This might be due to decreased production of IFN-γ in IL-12-deficient mice. Alth...

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Autors principals: Hultgren, Olof H, Stenson, Martin, Tarkowski, Andrzej
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17823/
https://ncbi.nlm.nih.gov/pubmed/11178125
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