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Deletion is neither sufficient nor necessary for the induction of peripheral tolerance in mature CD8(+) T cells

Previous reports have demonstrated clonal deletion of CD8(+) T cells during peripheral tolerance induction to tissue antigens. However, direct evidence demonstrating a causal connection between deletion and tolerance has not been reported because of model limitations in which the tissue antigens wer...

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Bibliografiske detaljer
Main Authors: Lees, Jason R, Charbonneau, Bridget, Swanson, Axel K, Jensen, Robert, Zhang, JianFeng, Matusik, Robert, Ratliff, Timothy L
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782220/
https://ncbi.nlm.nih.gov/pubmed/16423061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02293.x
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