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Deletion is neither sufficient nor necessary for the induction of peripheral tolerance in mature CD8(+) T cells
Previous reports have demonstrated clonal deletion of CD8(+) T cells during peripheral tolerance induction to tissue antigens. However, direct evidence demonstrating a causal connection between deletion and tolerance has not been reported because of model limitations in which the tissue antigens wer...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Blackwell Science Inc
2006
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782220/ https://ncbi.nlm.nih.gov/pubmed/16423061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02293.x |
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