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Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor

CD200 (OX2) is a membrane glycoprotein that interacts with a structurally related receptor (CD200R) involved in the regulation of macrophage function. The interaction is of low affinity (K(D) ∼ 1 μm) but can be detected using CD200 displayed in a multivalent form on beads or with dimeric fusion prot...

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Main Authors: Voulgaraki, Despina, Mitnacht-Kraus, Rita, Letarte, Michelle, Foster-Cuevas, Mildred, Brown, Marion H, Neil Barclay, A
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782167/
https://ncbi.nlm.nih.gov/pubmed/15946251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02161.x
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