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How do follicular dendritic cells interact intimately with B cells in the germinal centre?
The germinal centre is a dynamic microenvironment where antigen-activated B cells rapidly expand and differentiate, generating plasma cells and memory B cells. These cellular events are accompanied by dramatic changes in the antibody molecules that undergo somatic hypermutation and isotype switching...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782056/ https://ncbi.nlm.nih.gov/pubmed/15606789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.02075.x |
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