Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic influence on susceptibility and disease course. Cytokines play an important role in MS pathophysiology, and genes encoding various cytokines are logical candidates to assess possible associations with MS susce...

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Main Authors: Schrijver, Hans M, van As, Jaco, Crusius, J Bart A, Dijkstra, Christien D, Uitdehaag, Bernard M J
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781595/
https://ncbi.nlm.nih.gov/pubmed/12775358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0962933031000097691
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