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Dexamethasone prevents interleukin-1beta-induced nuclear factor-kappaB activation by upregulating IkappaB-alpha synthesis, in lymphoblastic cells.

AIMS: Glucocorticoids (GCs) exert some of their anti-inflammatory actions by preventing the activation of the transcription factor nuclear factor (NF)-kappaB. The GC-dependent inhibition of NF-kappaB may occur at different levels, but the mechanisms involved are still incompletely understood. In thi...

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Bibliografske podrobnosti
Main Authors: Castro-Caldas, M, Mendes, A F, Carvalho, A P, Duarte, C B, Lopes, M C
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781587/
https://ncbi.nlm.nih.gov/pubmed/12745547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0962935031000096953
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