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Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

BACKGROUND: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating variability of gene expression measurements in microarray experiments is essential for correctly identifying differentiall...

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Bibliografiske detaljer
Main Authors: Sartor, Maureen A, Tomlinson, Craig R, Wesselkamper, Scott C, Sivaganesan, Siva, Leikauf, George D, Medvedovic, Mario
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781470/
https://ncbi.nlm.nih.gov/pubmed/17177995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-538
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