Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells

Epigenetic silencing of regulatory genes by aberrant methylation contributes to tumorigenesis. DNA methyltransferase inhibitors (DNMTI) represent promising new drugs for anti-cancer therapies. The DNMTI 5-Azacytidine is effective against myelodysplastic syndrome, but induces switching of latent to l...

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Bibliographische Detailangaben
Hauptverfasser: Rao, Sieta P, Rechsteiner, Markus P, Berger, Christoph, Sigrist, Jürg A, Nadal, David, Bernasconi, Michele
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781464/
https://ncbi.nlm.nih.gov/pubmed/17214905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-3
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