P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling

BACKGROUND: Hyperglycemia or hyperinsulinemia contributes to poorer endometrial cancer survival. It was shown that P-LAP/IRAP translocates to the plasma membrane in response to insulin stimulation. Recently, we demonstrated that P-LAP/IRAP is associated with a poor prognosis in endometrial adenocarc...

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Hauptverfasser: Shibata, Kiyosumi, Kajiyama, Hiroaki, Ino, Kazuhiko, Nawa, Akihiro, Nomura, Seiji, Mizutani, Shigehiko, Kikkawa, Fumitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781462/
https://ncbi.nlm.nih.gov/pubmed/17233921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-15
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