Collagen reorganization at the tumor-stromal interface facilitates local invasion

BACKGROUND: Stromal-epithelial interactions are of particular significance in breast tissue as misregulation of these interactions can promote tumorigenesis and invasion. Moreover, collagen-dense breast tissue increases the risk of breast carcinoma, although the relationship between collagen density...

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Main Authors: Provenzano, Paolo P, Eliceiri, Kevin W, Campbell, Jay M, Inman, David R, White, John G, Keely, Patricia J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781458/
https://ncbi.nlm.nih.gov/pubmed/17190588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-4-38
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