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The role of specific 2′-hydroxyl groups in the stabilization of the folded conformation of kink-turn RNA
The role of 2′-hydroxyl groups in stabilizing the tightly kinked geometry of the kink-turn (K-turn) has been investigated. Individual 2′-OH groups have been removed by chemical synthesis, and the kinking of the RNA has been studied by gel electrophoresis and fluorescence resonance energy transfer. T...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1781366/ https://ncbi.nlm.nih.gov/pubmed/17158708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.285707 |
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