Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis

INTRODUCTION: In cancer the gelatinases [matrix metalloproteinase (MMP)-2 and MMP-9] have been shown to be associated with tissue invasion and metastatic disease. In patients with inflammatory arthritis the gelatinases are expressed in the synovial membrane, and have been implicated in synovial tiss...

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Autori principali: Goldbach-Mansky, Raphaela, Lee, Jennifer M, Hoxworth, Joseph M, Smith II, David, Duray, Paul, Schumacher, Ralph H, Yarboro, Cheryl H, Klippel, John, Kleiner, David, El-Gabalawy, Hani S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2000
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Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17808/
https://ncbi.nlm.nih.gov/pubmed/11062605
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