Fas-Mediated Apoptosis in Cholangiocarcinoma Cells Is Enhanced by 3,3′-Diindolylmethane through Inhibition of AKT Signaling and FLICE-Like Inhibitory Protein

4Stimulation of Fas-mediated apoptosis has been promoted as a potential therapy for many cancers, including cholangiocarcinoma. We have previously reported that Fas-resistant, but not Fas-sensitive, cholangiocarcinoma cells are tumorigenic in nude mice. The present studies sought to identify molecul...

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Detalhes bibliográficos
Main Authors: Chen, Yabing, Xu, Jianmin, Jhala, Nirag, Pawar, Pritish, Zhu, Zeng B., Ma, Liping, Byon, Chang-Hyun, McDonald, Jay M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780198/
https://ncbi.nlm.nih.gov/pubmed/17071604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060234
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