Insulin-Like Growth Factor-Binding Protein-5 Induces Pulmonary Fibrosis and Triggers Mononuclear Cellular Infiltration

We have recently shown that insulin-like growth factor-binding protein (IGFBP)-5 is overexpressed in idiopathic pulmonary fibrosis lung tissues and increases collagen and fibronectin deposition. Here, we further examined the effect of IGFBP-5 in vivo by intratracheal administration of replication-de...

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Bibliographische Detailangaben
Hauptverfasser: Yasuoka, Hidekata, Zhou, Zhihong, Pilewski, Joseph M., Oury, Tim D., Choi, Augustine M.K., Feghali-Bostwick, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2006
Schlagworte:
Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780193/
https://ncbi.nlm.nih.gov/pubmed/17071587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060501
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