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Liposome reconstitution and modulation of recombinant N-methyl-d-aspartate receptor channels by membrane stretch

In this study, the heteromeric N-methyl-d-aspartate (NMDA) receptor channels composed of NR1a and NR2A subunits were expressed, purified, reconstituted into liposomes, and characterized by using the patch clamp technique. The protein exhibited the expected electrophysiological profile of activation...

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Detalhes bibliográficos
Main Authors: Kloda, Anna, Lua, Linda, Hall, Rhonda, Adams, David J., Martinac, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780071/
https://ncbi.nlm.nih.gov/pubmed/17242368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609649104
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