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Structural rearrangements in the membrane penetration protein of a non-enveloped virus

Non-enveloped virus particles (those that lack a lipid-bilayer membrane) must breach the membrane of a target host cell to gain access to its cytoplasm. So far, the molecular mechanism of this membrane penetration step has resisted structural analysis. The spike protein VP4 is a principal component...

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Detalhes bibliográficos
Main Authors: Dormitzer, Philip R., Nason, Emma B., Venkataram Prasad, B. V., Harrison, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780043/
https://ncbi.nlm.nih.gov/pubmed/15329727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02836
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