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Synonymous codon selection controls in vivo turnover and amount of mRNA in Escherichia coli bla and ompA genes.

A number of silent codon changes were made in two Escherichia coli genes. For the ompA gene, the replacement of seven consecutive frequently used codons with synonymous infrequently used codons reduced the ompA mRNA level and its half-life. For the bla gene, the exchange of 24 codons for the most fr...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Deana, A, Ehrlich, R, Reiss, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8626345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.9.2718-2720.1996
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