Effects of divalent cations and spermine on the K(+) channel TASK-3 and on the outward current in thalamic neurons

The potassium channels TASK-1 and TASK-3 show high sequence homology but differ in their sensitivity to extracellular divalent cations. Heterologous expression in HEK293 cells showed that the single-channel conductance of TASK-3 increased approximately four-fold after removal of external divalent ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Musset, Boris, Meuth, Sven G, Liu, Gong Xin, Derst, Christian, Wegner, Sven, Pape, Hans-Christian, Budde, Thomas, Preisig-Müller, Regina, Daut, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2006
Schlagworte:
Molecular and Genomic
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780017/
https://ncbi.nlm.nih.gov/pubmed/16513667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.106898
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