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Membrane Assembly of Simple Helix Homo-Oligomers Studied via Molecular Dynamics Simulations

The assembly of simple transmembrane helix homo-oligomers is studied by combining a generalized Born implicit membrane model with replica exchange molecular dynamics simulations to sample the conformational space of various oligomerization states and the native oligomeric conformation. Our approach...

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Hlavní autoři: Bu, Lintao, Im, Wonpil, Brooks, Charles L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779983/
https://ncbi.nlm.nih.gov/pubmed/17085501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095216
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