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Cholesterol Surrogates: A Comparison of Cholesterol and 16:0 Ceramide in POPC Bilayers

Experimental evidence indicates that, under some circumstances, “surrogate” molecules may play the same role as cholesterol in ordering membrane lipids. The simplest molecule in this class is Ceramide. In this article, we describe atomic-level molecular dynamics simulations designed to shed light on...

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Auteurs principaux: Pandit, Sagar A., Chiu, See-Wing, Jakobsson, Eric, Grama, Ananth, Scott, H. L.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779968/
https://ncbi.nlm.nih.gov/pubmed/17071659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095034
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