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Cholesterol Surrogates: A Comparison of Cholesterol and 16:0 Ceramide in POPC Bilayers

Experimental evidence indicates that, under some circumstances, “surrogate” molecules may play the same role as cholesterol in ordering membrane lipids. The simplest molecule in this class is Ceramide. In this article, we describe atomic-level molecular dynamics simulations designed to shed light on...

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Bibliographic Details
Main Authors: Pandit, Sagar A., Chiu, See-Wing, Jakobsson, Eric, Grama, Ananth, Scott, H. L.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779968/
https://ncbi.nlm.nih.gov/pubmed/17071659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095034
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