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Analysis of Two-Dimensional Dissociation Constant of Laterally Mobile Cell Adhesion Molecules

We formulate a general analysis to determine the two-dimensional dissociation constant (2D K(d)), and use this method to study the interaction of CD2-expressing T cells with glass-supported planar bilayers containing fluorescently labeled CD58, a CD2 counter-receptor. Both CD2 and CD58 are laterally...

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Detalles Bibliográficos
Main Authors: Zhu, De-Min, Dustin, Michael L., Cairo, Christopher W., Golan, David E.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779959/
https://ncbi.nlm.nih.gov/pubmed/17085486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.089649
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