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Apical Localization of Sodium-Dependent Glucose Transporter SGLT1 is Maintained by Cholesterol and Microtubules

A GFP-labeled sodium-dependent glucose transporter SGLT1 (SGLT-GFP) was transfected into MDCK cells. SGLT-GFP was localized at the apical membrane in confluent cells. When cellular cholesterol was depleted by methyl-β-cyclodextrin (MβCD) treatment, the localization of SGLT-GFP gradually switched fro...

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Detalhes bibliográficos
Main Authors: Suzuki, Takeshi, Matsuzaki, Toshiyuki, Hagiwara, Haruo, Aoki, Takeo, Tajika-Takahashi, Yukiko, Takata, Kuniaki
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Society of Histochemistry and Cytochemistry 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779948/
https://ncbi.nlm.nih.gov/pubmed/17327902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.06024
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