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Antagonistic Effects of Cofilin, Beryllium Fluoride Complex, and Phalloidin on Subdomain 2 and Nucleotide-Binding Cleft in F-Actin

Cofilin/ADF, beryllium fluoride complex (BeFx), and phalloidin have opposing effects on actin filament structure and dynamics. Cofilin/ADF decreases the stability of F-actin by enhancing disorder in subdomain 2, and by severing and accelerating the depolymerization of the filament. BeFx and phalloid...

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Main Authors: Muhlrad, Andras, Ringel, Israel, Pavlov, Dmitry, Peyser, Y. Michael, Reisler, Emil
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779938/
https://ncbi.nlm.nih.gov/pubmed/16997870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.087767
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