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Direct Measurement of Local Chromatin Fluidity Using Optical Trap Modulation Force Spectroscopy
Chromatin assembly is condensed by histone tail-tail interactions and other nuclear proteins into a highly compact structure. Using an optical trap modulation force spectroscopy, we probe the effect of tail interactions on local chromatin fluidity. Chromatin fibers, purified from mammalian cells, ar...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Biophysical Society
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1779931/ https://ncbi.nlm.nih.gov/pubmed/17012315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.086827 |
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