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Structure-Function Analysis of Tritrpticin Analogs: Potential Relationships between Antimicrobial Activities, Model Membrane Interactions, and Their Micelle-Bound NMR Structures

Tritrpticin is a member of the cathelicidin family of antimicrobial peptides. Starting from its native sequence (VRRFPWWWPFLRR), eight synthetic peptide analogs were studied to investigate the roles of specific residues in its biological and structural properties. This included amidation of the C-te...

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Bibliografiske detaljer
Main Authors: Schibli, David J., Nguyen, Leonard T., Kernaghan, Stephanie D., Rekdal, Øystein, Vogel, Hans J.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779919/
https://ncbi.nlm.nih.gov/pubmed/16997878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085837
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