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Structure-Function Analysis of Tritrpticin Analogs: Potential Relationships between Antimicrobial Activities, Model Membrane Interactions, and Their Micelle-Bound NMR Structures

Tritrpticin is a member of the cathelicidin family of antimicrobial peptides. Starting from its native sequence (VRRFPWWWPFLRR), eight synthetic peptide analogs were studied to investigate the roles of specific residues in its biological and structural properties. This included amidation of the C-te...

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Detalhes bibliográficos
Main Authors: Schibli, David J., Nguyen, Leonard T., Kernaghan, Stephanie D., Rekdal, Øystein, Vogel, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779919/
https://ncbi.nlm.nih.gov/pubmed/16997878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085837
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