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Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis.

We have examined the effect of replacing umuDC with mucAB or rumAB on the mutagenic properties of a T-T cyclobutane dimer in an attempt to determine the molecular basis for the differences in UV-induced mutagenesis that are associated with these structurally and functionally related genes. A single-...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Szekeres, E S, Woodgate, R, Lawrence, C W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8626322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.9.2559-2563.1996
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