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Phenotypes of Myopathy-related Actin Mutants in differentiated C2C12 Myotubes

BACKGROUND: About 20 % of nemaline myopathies are thus far related to skeletal muscle alpha-actin. Seven actin mutants located in different parts of the actin molecule and linked to different forms of the disease were selected and expressed as EGFP-tagged constructs in differentiated C2C12 mytoubes....

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Bibliografske podrobnosti
Main Authors: Bathe, Friederike S, Rommelaere, Heidi, Machesky, Laura M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779783/
https://ncbi.nlm.nih.gov/pubmed/17227580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-2
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