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Ca(2+)-desensitizing hypoxic vasorelaxation: pivotal role for the myosin binding subunit of myosin phosphatase (MYPT1) in porcine coronary artery

Acute hypoxia dilates most systemic arteries leading to increased tissue perfusion. We showed that at high stimulus conditions, porcine coronary artery was relaxed by hypoxia without a change in [Ca(2+)](i). This ‘Ca(2+)-desensitizing hypoxic relaxation’ was validated in permeabilized porcine corona...

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Detalhes bibliográficos
Main Authors: Wardle, Robert L, Gu, Min, Ishida, Yukisato, Paul, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779640/
https://ncbi.nlm.nih.gov/pubmed/16439434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.104083
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