Isolation of a pdxJ point mutation that bypasses the requirement for the PdxH oxidase in pyridoxal 5' -phosphate coenzyme biosynthesis in Escherichia coli K-12.
We isolated 26 suppressor mutations that allowed growth of a delta pdxH::omega null mutant in the absence of pyridoxal. Each suppressor mapped to pdxJ, and the eight suppressors sequenced contained the same glycine-to-serine change in the PdxJ polypeptide. This bypass suppression suggests that PdxJ...
Salvato in:
| Pubblicato in: | J Bacteriol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1996
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.8.2445-2449.1996 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|