A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

Recently, approaches have been developed for high-throughput identification of synthetic sick/lethal gene pairs. However, these are only a specific example of the broader phenomenon of epistasis, wherein the presence of one mutation modulates the phenotype of another. We present analysis techniques...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Collins, Sean R, Schuldiner, Maya, Krogan, Nevan J, Weissman, Jonathan S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2006
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779568/
https://ncbi.nlm.nih.gov/pubmed/16859555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-7-r63
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