Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series study

INTRODUCTION: The cytotoxic effects of radiation therapy are mediated primarily through increased formation of hydroxyl radicals and reactive oxygen species, which can damage cells, proteins and DNA; the glutathione S-transferases (GSTs) function to protect against oxidative stress. We hypothesized...

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Main Authors: Ambrosone, Christine B, Tian, Chunqiao, Ahn, Jiyoung, Kropp, Silke, Helmbold, Irmgard, von Fournier, Dietrich, Haase, Wulf, Sautter-Bihl, Marie Luise, Wenz, Frederik, Chang-Claude, Jenny
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779469/
https://ncbi.nlm.nih.gov/pubmed/16848913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1526
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